Postdoc (all genders) for Computational Immunology

Main tasks

At the Hamburg Center for Translational Immunology (HCTI) within the University Medical Center Hamburg-Eppendorf (UKE), we are actively seeking highly motivated postdoctoral candidates with a robust background in computational immunology as part of the lab of Nicola Gagliani (UKE - HCTI - Startseite)

Our research focus centers on investigating the fundamental molecular and cellular mechanisms of T cell biology. Specifically, we explore how T cells adapt to environmental changes and ultimately contribute to either mediating physiological responses to pathogens or engaging in pathological tissue-damaging processes (Vesely et al., Cell (2019), Zhao Yu et al., Science Immunology (2021), Tintelnot J. et al., Nature (2023), Siracusa F. et al., Nature Immunology (2023), and Siracusa F. et al., Trends in Immunology (2023)).

In the upcoming years, we are dedicated to use systems immunology to decode the intricate interplay between environmental triggers and the immune system, with a specific emphasis on T cells resident in the different organs. Our research aims to elucidate how these organ-resident T cells adapt to various tissues and consequently influence the development of both physiological and pathological immune responses, including tumor development. A key aspect of this project is to use and develop new compuatational tools to transform big data into knlowdge.

The laboratory of Nicola Gagliani is funded by DFG and ERC, providing a unique opportunity for fellows to access a combination of state-of-the-art techniques and multiomics data to answer key biological questions.

This position is initially limited until 29.3.2029 for project-related reasons.

Your Profile

• PhD or MD or an equivalent degree
• expertise and commitment to computational biology, particular in T cells
• Experience in analyzing high-throughput sequencing data, single-cell or spatial data sets, in statistical data analysis, integration, and visualization
• fluency in at least one data science language (R, Python, Matlab)

Immunity status

Please note that employment is contingent upon proof of immunization or immunity against the measles virus, in accordance with applicable legal and medical requirements. Documentation (e.g., vaccination certificate) must be provided before employment begins.

Our Offer

• International and multidisciplinary environment at the University Medical Center Hamburg-Eppendorf, a leading institution in Europe (Germany).
• Possibility to collaborate and being co-supervised with Prof. Jan Baumbach, Computational Systems Biology Lab, (UHH, Hamburg) to further improve the computational expertise.
• Access to the institution's soft skills program, including training in presenting skills and scientific writing, as well as career-oriented courses.
• Mentoring focused on building the best possible career within and outside academia.
• Weekly scientific exchange through lab meetings and journal clubs.
• Opportunity to collaborate with research groups at the University of Yale (USA) and the Karolinska Institute (Sweden).
• Attractive compensation according to TVöD/VKA
• Secure employment with meaningful work and respectful collaboration
• Comprehensive onboarding and open knowledge exchange within the team
• Extensive training and further education programs at our UKE Academy for Education and Careers
• Opportunities to contribute to our “UKE INside” personnel policy through cross-professional and cross-hierarchical projects
• Sustainable travel: subsidies for the Deutschlandticket as a job ticket, and Dr. Bike bicycle service
• Family-friendly working environment: cooperation on childcare, free vacation childcare, advice for employees with relatives in need of care
• Excellent health, wellness, and sports programs
• A wide range of dining options in our staff restaurant, with additional choices available at the “Health Kitchen” cafés, bistros, and an on-site supermarket